Voiceover
It’s frustrated when you’re trying to say something and are muted.
It’s worse when you’re trying to say something and your players won’t mute.
The way speakers and most VOIP are set-up, when more than one person is talking you hear nothing. There’s just overlap and noise. It inevitably happens sometimes: even with web cameras there’s a lack of body language and cues that someone’s trying to talk. And there’s that 5-second delay between you starting to talk and realizing someone eIse is talking at the same time, where you potentially both stop and then start again, like people continually blocking each other when trying to walk down a sidewalk.
But it’s extra frustrating when important descriptions or plot advancing questions are being killed so someone can make a “deez nuts” joke.
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You should learn about advanced role-playing communication from the D&D Ultimate Edition Dungeon Master’s Guide: https://culture.vg/forum/topic?f=28&t=7280
More chapters are linked off here: http://dndbattlegrounds.net/
It solves the problem entirely (plus many others, that for example the players aren’t good actors and hence shouldn’t be voice acting, etc.)